{"id":8086,"date":"2026-07-16T17:58:21","date_gmt":"2026-07-16T09:58:21","guid":{"rendered":"http:\/\/www.bio-oi.com\/?p=8086"},"modified":"2026-07-17T13:39:04","modified_gmt":"2026-07-17T05:39:04","slug":"8086","status":"publish","type":"post","link":"https:\/\/www.bio-oi.com\/?p=8086","title":{"rendered":"\u57fa\u4e8e\u79f8\u79c6\u589e\u5f3a\u9ecf\u571f\u4eff\u751f\u539f\u7406\u7684\u590d\u5408\u6c34\u51dd\u80f6\u901a\u8fc7\u8c03\u63a7\u514d\u75ab-\u6210\u9aa8\u7ea7\u8054\u53cd\u5e94\u53ca\u7ebf\u7c92\u4f53\u7a33\u6001\u91cd\u5851\u4fc3\u8fdb\u7cd6\u5c3f\u75c5\u6027\u9aa8\u518d\u751f"},"content":{"rendered":"<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.bio-oi.com\/wp-content\/uploads\/2026\/07\/ACS1-1024x486.png\" alt=\"\" width=\"800\" height=\"380\" \/><\/span><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u8fd1\u671f\u4e00\u9879\u7814\u7a76\u663e\u793a\u53d7\u201c\u79f8\u79c6\u589e\u5f3a\u9ecf\u571f\u201d\u7ed3\u6784\u542f\u53d1\uff0c\u8bbe\u8ba1\u4e86\u4e00\u79cd\u6d3b\u6027\u6c27\uff08ROS\uff09\u54cd\u5e94\u6027\u590d\u5408\u6c34\u51dd\u80f6\uff08EM@mSF-AP\uff09\uff0c\u7528\u4e8e\u7cd6\u5c3f\u75c5\u9aa8\u7f3a\u635f\u4fee\u590d\u3002\u8be5\u6c34\u51dd\u80f6\u4ee5\u787c\u9178\u916f\u952e\u4e3a\u4ea4\u8054\u7f51\u7edc\uff0c\u63ba\u5165\u77ff\u5316\u4e1d\u7d20\u86cb\u767d\u77ed\u7ea4\u7ef4\uff08mSF\uff09\u589e\u5f3a\u529b\u5b66\u6027\u80fd\u5e76\u91ca\u653e\u4fc3\u8840\u7ba1\/\u6210\u9aa8\u79bb\u5b50\uff0c\u540c\u65f6\u8d1f\u8f7dEGCG-Met\u7eb3\u7c73\u7c92\uff08EM NPs\uff09\u3002\u5728\u9ad8ROS\u5fae\u73af\u5883\u4e2d\uff0c\u6c34\u51dd\u80f6\u667a\u80fd\u91ca\u653eEM NPs\uff0c\u6e05\u9664ROS\u5e76\u8bf1\u5bfc\u5de8\u566c\u7ec6\u80deM2\u6781\u5316\uff0c\u8fdb\u800c\u9a71\u52a8\u514d\u75ab-\u6210\u9aa8\u7ea7\u8054\u53cd\u5e94\uff0c\u7cfb\u7edf\u6027\u6062\u590d\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08BMSCs\uff09\u7ebf\u7c92\u4f53\u7a33\u6001\uff08\u6fc0\u6d3bSod2-Cat\u6297\u6c27\u5316\u8f74\u3001\u6062\u590d\u819c\u7535\u4f4d\u4e0e\u52a8\u6001\u5e73\u8861\u3001\u4e0a\u8c03COX IV\u589e\u5f3a\u80fd\u91cf\u4ee3\u8c22\uff09\u3002mSF\u534f\u540c\u4fc3\u8fdb\u8840\u7ba1\u751f\u6210\u4e0e\u6210\u9aa8\u5206\u5316\u3002\u52a8\u7269\u5b9e\u9a8c\u8bc1\u5b9e\uff0c\u8be5\u6c34\u51dd\u80f6\u5728\u7cd6\u5c3f\u75c5\u5927\u9f20\u9885\u9aa8\u7f3a\u635f\u6a21\u578b\u4e2d\u663e\u8457\u6539\u5584\u514d\u75ab\u5fae\u73af\u5883\u3001\u589e\u5f3a\u80fd\u91cf\u4ee3\u8c22\u3001\u4fc3\u8fdb\u65b0\u9aa8\u5f62\u6210\u3002<\/span>\u00a0<\/section>\n<p><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u76f8\u5173\u6210\u679c\u4ee5\u201c<strong>A Straw-Reinforced-Clay-Inspired Composite Hydrogel Promotes Diabetic Bone Regeneration via Driving the Immune-Osteogenic Cascade to Remodel Mitochondrial Homeostasis\u201d<\/strong>\u4e3a\u9898\u53d1\u8868\u4e8e<strong>\u300aACS Nano\u300b\uff08IF=17.3\uff09\uff0c\u897f\u5357\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u53e3\u8154\u533b\u9662\u9676\u521a\u3001\u8d75\u4e39\u3001\u8521\u854a\u4e3a\u5171\u540c\u901a\u8baf\u4f5c\u8005<\/strong>\u3002<\/span><\/p>\n<section><\/section>\n<h1 style=\"text-align: center;\"><span style=\"font-size: 14pt; color: #3366ff;\"><strong><span style=\"font-family: arial, helvetica, sans-serif;\">\u6587\u7ae0\u521b\u65b0\u70b9<\/span><\/strong><\/span><\/h1>\n<section><\/section>\n<section><\/section>\n<section><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u57fa\u4e8e\u79f8\u79c6\u589e\u5f3a\u7c98\u571f\u7ed3\u6784\u7684\u542f\u53d1\u8bbe\u8ba1\u4e86\u4e00\u79cd\u6d3b\u6027\u6c27\uff08ROS\uff09\u54cd\u5e94\u6027\u590d\u5408\u6c34\u51dd\u80f6\uff08EM@mSF-AP\uff09\uff0c\u7528\u4e8e\u7cd6\u5c3f\u75c5\u9aa8\u7f3a\u635f\u4fee\u590d\u3002\u8be5\u7814\u7a76\u63d0\u51fa\u201c\u514d\u75ab\u8c03\u63a7\u2014\u7ebf\u7c92\u4f53\u7a33\u6001\u6062\u590d\u2014\u6210\u9aa8\u8026\u5408\u201d\u7ea7\u8054\u6cbb\u7597\u7b56\u7565\uff0c\u4e3a\u7cd6\u5c3f\u75c5\u9aa8\u518d\u751f\u63d0\u4f9b\u4e86\u65b0\u601d\u8def\u3002<\/span><\/section>\n<p>&nbsp;<\/p>\n<section>\n<section>\n<section>\n<section><\/section>\n<section><\/section>\n<h2><span style=\"color: #ff9900;\"><strong><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u79f8\u79c6\u589e\u5f3a\u7c98\u571f\u7ed3\u6784\u7684\u539f\u7406<\/span><\/strong><\/span><\/h2>\n<section data-width=\"60%\"><\/section>\n<\/section>\n<\/section>\n<section>\n<section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><strong>\u589e\u5f3a\u673a\u5236\uff1a<\/strong>\u5c06\u9ad8\u957f\u5f84\u6bd4\u3001\u9ad8\u6297\u62c9\u5f3a\u5ea6\u7684\u7ea4\u7ef4\u76f8\uff08\u201c\u79f8\u79c6\u201d\uff09\u5747\u5300\u5206\u6563\u4e8e\u57fa\u4f53\u76f8\uff08\u201c\u9ecf\u571f\u201d\uff09\u4e2d\uff0c\u4f7f\u590d\u5408\u6750\u6599\u517c\u5177\u57fa\u4f53\u7684\u8fde\u7eed\u6027\u4e0e\u7ea4\u7ef4\u7684\u97e7\u6027\uff0c\u5f25\u8865\u57fa\u4f53\u5728\u6297\u62c9\u3001\u6297\u88c2\u65b9\u9762\u7684\u4e0d\u8db3\u3002<\/span><\/section>\n<\/section>\n<\/section>\n<section>\n<section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><strong>\u8f7d\u8377\u4f20\u9012\uff1a<\/strong>\u7ea4\u7ef4\u4e0e\u57fa\u4f53\u95f4\u7684\u754c\u9762\u7ed3\u5408\u5f3a\u5ea6\u51b3\u5b9a\u589e\u5f3a\u6548\u7387\u3002\u8f7d\u8377\u901a\u8fc7\u754c\u9762\u7531\u57fa\u4f53\u4f20\u9012\u81f3\u7ea4\u7ef4\uff0c\u826f\u597d\u7684\u754c\u9762\u7ed3\u5408\u53ef\u4f7f\u7ea4\u7ef4\u6709\u6548\u627f\u8f7d\u5e94\u529b\uff0c\u4ece\u800c\u63d0\u5347\u6574\u4f53\u529b\u5b66\u6027\u80fd\u3002<\/span><\/section>\n<\/section>\n<\/section>\n<section>\n<section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><strong>\u589e\u97e7\u6297\u88c2\uff1a<\/strong>\u7ea4\u7ef4\u901a\u8fc7\u201c\u6865\u63a5\u201d\u4f5c\u7528\u963b\u788d\u88c2\u7eb9\u6269\u5c55\uff0c\u5e76\u8bf1\u5bfc\u88c2\u7eb9\u504f\u8f6c\uff0c\u589e\u52a0\u65ad\u88c2\u80fd\u8017\uff1b\u540c\u65f6\uff0c\u7ea4\u7ef4\u7f51\u7edc\u5728\u57fa\u4f53\u5185\u5f62\u6210\u7a7a\u95f4\u9aa8\u67b6\uff0c\u589e\u5f3a\u7ed3\u6784\u6574\u4f53\u6027\u4e0e\u7a33\u5b9a\u6027\u3002<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<section><\/section>\n<section><\/section>\n<h1 style=\"text-align: center;\"><span style=\"color: #3366ff;\"><strong><span style=\"font-family: arial, helvetica, sans-serif; font-size: 14pt;\">\u6587\u7ae0\u4e3b\u8981\u601d\u8def<\/span><\/strong><\/span><\/h1>\n<section>\n<section>\n<h2><span style=\"color: #ff9900;\"><strong><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">1. \u95ee\u9898\u5bfc\u5411\uff1a\u660e\u786e\u75c5\u7406\u673a\u5236<\/span><\/strong><\/span><\/h2>\n<\/section>\n<section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u7814\u7a76\u9996\u5148\u9610\u660e\u7cd6\u5c3f\u75c5\u9aa8\u4fee\u590d\u969c\u788d\u7684\u5173\u952e\u73af\u8282\uff1a\u9ad8\u8840\u7cd6\u5fae\u73af\u5883\u8bf1\u5bfc\u5de8\u566c\u7ec6\u80de\u7ebf\u7c92\u4f53\u529f\u80fd\u969c\u788d\uff0c\u4fc3\u4f7f\u5176\u5411\u4fc3\u708eM1\u8868\u578b\u6781\u5316\uff0c\u8fdb\u800c\u901a\u8fc7\u65c1\u5206\u6ccc\u4fe1\u53f7\u5e72\u6270BMSCs\u7ebf\u7c92\u4f53\u7a33\u6001\uff08\u6c27\u5316\u5e94\u6fc0\u52a0\u5267\u3001\u80fd\u91cf\u4ee3\u8c22\u6291\u5236\uff09\uff0c\u6700\u7ec8\u524a\u5f31\u6210\u9aa8\u5206\u5316\u80fd\u529b\u3002\u7531\u6b64\u63d0\u51fa\u201c\u4fee\u590d\u514d\u75ab-\u6210\u9aa8\u7ea7\u8054\u201d\u4e0e\u201c\u91cd\u5851\u7ebf\u7c92\u4f53\u7a33\u6001\u201d\u5e76\u884c\u7684\u6cbb\u7597\u5047\u8bf4\u3002<\/span><\/section>\n<\/section>\n<section>\n<section>\n<section>\n<section><\/section>\n<section><\/section>\n<h2><strong><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt; color: #ff9900;\">2. \u6750\u6599\u8bbe\u8ba1\uff1a\u4eff\u751f\u7ed3\u6784\u4e0e\u529f\u80fd\u96c6\u6210<\/span><\/strong><\/h2>\n<\/section>\n<section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u53d7\u201c\u79f8\u79c6\u589e\u5f3a\u9ecf\u571f\u201d\u7ed3\u6784\u542f\u53d1\uff0c\u5c06\u77ff\u5316\u63ba\u9536\u7f9f\u57fa\u78f7\u7070\u77f3\u7684\u4e1d\u7d20\u86cb\u767d\u77ed\u7ea4\u7ef4\uff08mSF\uff09\u4f5c\u4e3a\u589e\u5f3a\u76f8\u5f15\u5165\u787c\u9178\u916f\u4ea4\u8054\u7684ROS\u54cd\u5e94\u6027\u6c34\u51dd\u80f6\uff08AP\uff09\u4e2d\uff0c\u540c\u65f6\u8d1f\u8f7dEGCG-Met\u7eb3\u7c73\u7c92\uff08EM NPs\uff09\u3002\u8be5\u8bbe\u8ba1\u8d4b\u4e88\u6750\u6599\u4e09\u91cd\u529f\u80fd\uff1a<\/span><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><span style=\"color: #ff9900;\">\u25b6<\/span> mSF\u7ea4\u7ef4\u7f51\u7edc\u63d0\u5347\u529b\u5b66\u5f3a\u5ea6\u5e76\u5ef6\u7f13\u964d\u89e3\uff0c\u63d0\u4f9b\u6301\u7eed\u7269\u7406\u652f\u6491\uff1b<\/span><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><span style=\"color: #ff9900;\">\u25b6<\/span> EM NPs\u54cd\u5e94\u9ad8ROS\u5fae\u73af\u5883\u6309\u9700\u91ca\u653e\uff0c\u53d1\u6325\u6297\u6c27\u5316\u4e0e\u514d\u75ab\u8c03\u8282\u6d3b\u6027\uff1b<\/span><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><span style=\"color: #ff9900;\">\u25b6<\/span> mSF\u91ca\u653eSr\u00b2\u207a\/Ca\u00b2\u207a\u79bb\u5b50\u534f\u540c\u4fc3\u8fdb\u8840\u7ba1\u751f\u6210\u4e0e\u6210\u9aa8\u3002<\/span><\/section>\n<section><\/section>\n<h2><strong><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt; color: #ff9900;\">3. \u673a\u5236\u9a8c\u8bc1\uff1a\u7ea7\u8054\u8c03\u63a7\u8def\u5f84<\/span><\/strong><\/h2>\n<\/section>\n<\/section>\n<section>\n<section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u7814\u7a76\u901a\u8fc7\u4f53\u5916\u5171\u57f9\u517b\u4e0e\u8f6c\u5f55\u7ec4\u5b66\u5206\u6790\uff0c\u9010\u7ea7\u9a8c\u8bc1\u4e86\u6c34\u51dd\u80f6\u7684\u4f5c\u7528\u901a\u8def\uff1a<\/span><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><strong>\u514d\u75ab\u8c03\u63a7\u5c42\uff1a<\/strong>\u6e05\u9664ROS \u2192 \u4fee\u590d\u5de8\u566c\u7ec6\u80de\u7ebf\u7c92\u4f53\u529f\u80fd \u2192 \u4fc3\u8fdbM2\u6781\u5316\uff1b<\/span><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><strong>\u6210\u9aa8\u542f\u52a8\u5c42\uff1a<\/strong>M2\u5de8\u566c\u7ec6\u80de\u65c1\u5206\u6ccc\u4fe1\u53f7 \u2192 \u6fc0\u6d3bBMSCs\u4e2dSod2-Cat\u6297\u6c27\u5316\u8f74\u3001\u6062\u590d\u7ebf\u7c92\u4f53\u819c\u7535\u4f4d\u4e0e\u52a8\u6001\u5e73\u8861\u3001\u4e0a\u8c03COX IV\u589e\u5f3a\u6c27\u5316\u78f7\u9178\u5316 \u2192 \u7cfb\u7edf\u6027\u91cd\u5851\u7ebf\u7c92\u4f53\u7a33\u6001\u4e0e\u80fd\u91cf\u4ee3\u8c22\uff1b<\/span><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><strong>\u6548\u5e94\u653e\u5927\u5c42\uff1a<\/strong>mSF\u91ca\u653e\u7684\u751f\u7269\u6d3b\u6027\u79bb\u5b50\u76f4\u63a5\u589e\u5f3aBMSCs\u6210\u9aa8\u5206\u5316\u4e0e\u5185\u76ae\u7ec6\u80de\u8840\u7ba1\u5316\u3002<\/span><\/section>\n<section>\n<section>\n<section>\n<section>\n<section><\/section>\n<section><\/section>\n<h2><span style=\"color: #ff9900;\"><strong><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">4. \u8f6c\u5316\u9a8c\u8bc1\uff1a\u4f53\u5185\u529f\u80fd<\/span><\/strong><\/span><\/h2>\n<\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u5728\u7cd6\u5c3f\u75c5\u5927\u9f20\u9885\u9aa8\u7f3a\u635f\u6a21\u578b\u4e2d\uff0c\u6c34\u51dd\u80f6\u690d\u5165\u540e\u6709\u6548\u6539\u5584\u5c40\u90e8\u514d\u75ab\u5fae\u73af\u5883\u3001\u589e\u5f3a\u80fd\u91cf\u4ee3\u8c22\u3001\u4fc3\u8fdb\u65b0\u751f\u8840\u7ba1\u4e0e\u9aa8\u7ec4\u7ec7\u5f62\u6210\uff0c\u4ece\u7ec4\u7ec7\u5c42\u9762\u8bc1\u5b9e\u4e86\u201c\u514d\u75ab\u8c03\u63a7-\u7ebf\u7c92\u4f53\u7a33\u6001\u6062\u590d-\u6210\u9aa8\u8026\u5408\u201d\u7ea7\u8054\u7b56\u7565\u7684\u53ef\u884c\u6027\u3002<\/span><\/section>\n<section><\/section>\n<p>&nbsp;<\/p>\n<h1 style=\"text-align: center;\"><strong style=\"color: #3366ff; font-size: 14pt;\"><span style=\"font-family: arial, helvetica, sans-serif;\">\u6587\u7ae0\u90e8\u5206\u65b9\u6cd5\u5b66\u5256\u6790<\/span><\/strong><\/h1>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-8092\" src=\"https:\/\/www.bio-oi.com\/wp-content\/uploads\/2026\/07\/ACS2.png\" alt=\"\" width=\"500\" height=\"375\" srcset=\"https:\/\/www.bio-oi.com\/wp-content\/uploads\/2026\/07\/ACS2.png 1023w, https:\/\/www.bio-oi.com\/wp-content\/uploads\/2026\/07\/ACS2-300x225.png 300w, https:\/\/www.bio-oi.com\/wp-content\/uploads\/2026\/07\/ACS2-768x576.png 768w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><\/p>\n<p><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u6587\u4e2d\u5bf9Western blot\u8fdb\u884c\u4e86\u8be6\u7ec6\u7684\u65b9\u6cd5\u5b66\u4ecb\u7ecd\u4ee5\u53ca\u8fdb\u884c\u4e86Sod2\u3001Cat\u53caCOX IV\u86cb\u767d\u8868\u8fbe\u6c34\u5e73\u7684\u86cb\u767d\u8d28\u5370\u8ff9\u5206\u6790\uff1a\u4f7f\u7528\u6dfb\u52a0\u4e86\u86cb\u767d\u9176\u6291\u5236\u5242\u548c\u78f7\u9178\u9176\u6291\u5236\u5242\u7684RIPA\u88c2\u89e3\u6db2\uff0c\u5728\u51b0\u4e0a\u63d0\u53d6\u603b\u86cb\u767d\u3002\u88c2\u89e3\u7269\u7ecf\u8d85\u58f0\u5904\u7406\uff0c\u968f\u540e\u4e8e12,000 rpm\u79bb\u5fc3\u3002\u91c7\u7528BCA\u86cb\u767d\u5b9a\u91cf\u8bd5\u5242\u76d2\u6d4b\u5b9a\u86cb\u767d\u6d53\u5ea6\u3002\u53d6\u7b49\u91cf\u716e\u6cb8\u53d8\u6027\u7684\u86cb\u767d\u6837\u54c1\uff0c\u7ecf\u5341\u4e8c\u70f7\u57fa\u786b\u9178\u94a0-\u805a\u4e19\u70ef\u9170\u80fa\u51dd\u80f6\u7535\u6cf3\uff08SDS-PAGE\uff09\u5206\u79bb\uff0c\u5e76\u8f6c\u79fb\u81f3\u805a\u504f\u4e8c\u6c1f\u4e59\u70ef\uff08PVDF\uff09\u819c\u3002\u8f6c\u819c\u540e\uff0c\u4f7f\u7528\u65e0\u86cb\u767d\u5feb\u901f\u5c01\u95ed\u6db2\u4e8e\u5ba4\u6e29\u5c01\u95ed15\u5206\u949f\u3002\u968f\u540e\u5c06\u819c\u4e0e\u6297\u4f53Sod2\u3001\u6297\u4f53Cat\u3001\u6297\u4f53COX IV\u53ca\u6297\u4f53\u03b2-actin\u4e00\u6297\u4e8e4\u00b0C\u5b75\u80b2\u8fc7\u591c\u3002\u7ecf\u4e09\u6b21\u6d17\u6da4\u540e\uff0c\u5c06\u819c\u4e0e\u8fa3\u6839\u8fc7\u6c27\u5316\u7269\u9176\uff08HRP\uff09\u6807\u8bb0\u7684\u5c71\u7f8a\u6297\u5154IgG\u4e8c\u6297\u5b75\u80b2\u3002<strong>\u514d\u75ab\u53cd\u5e94\u86cb\u767d\u6761\u5e26\u901a\u8fc7\u5149\u4eeaOI600MF Touch\u5316\u5b66\u53d1\u5149\u591a\u8272\u8367\u5149\u6210\u50cf\u7cfb\u7edf\u663e\u5f71\u68c0\u6d4b\u3002<\/strong><\/span><\/p>\n<p><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u5f97\u51fa\u7ed3\u8bba\uff0c\u5728\u7cd6\u5c3f\u75c5\u9aa8\u7f3a\u635f\u7684\u75c5\u7406\u5fae\u73af\u5883\u4e2d\uff0c\u6301\u7eed\u6027\u9ad8\u8840\u7cd6\u53ef\u7834\u574f\u7ebf\u7c92\u4f53\u7a33\u6001\u3002<strong>EM@mSF-AP\u6c34\u51dd\u80f6\u901a\u8fc7\u5de8\u566c\u7ec6\u80de\u4ecb\u5bfc\u7684\u514d\u75ab-\u6c27\u5316\u7ea7\u8054\u8c03\u63a7\uff0c\u4e0d\u4ec5\u589e\u5f3a\u4e86BMSCs\u7684\u6c27\u5316\u5e94\u6fc0\u62b5\u6297\u80fd\u529b\u3001\u51cf\u8f7b\u4e86\u7ebf\u7c92\u4f53\u6c27\u5316\u635f\u4f24\uff0c\u8fd8\u6062\u590d\u4e86\u7535\u5b50\u4f20\u9012\u6548\u7387\u5e76\u4f18\u5316\u4e86\u80fd\u91cf\u4ee3\u8c22\u7ebf\u7c92\u4f53\u547c\u5438\u94fe\u590d\u5408\u7269IV\uff08COX IV\uff09\u3002<\/strong>COX IV\u4e3a\u7ebf\u7c92\u4f53\u547c\u5438\u94fe\u590d\u5408\u4f53\u2163\u7684\u5173\u952e\u8c03\u8282\u4e9a\u57fa\uff0c\u590d\u5408\u4f53\u2163\u662f\u7535\u5b50\u4f20\u9012\u94fe\u7684\u672b\u7aef\u6c27\u5316\u9176\uff0c\u5e38\u88ab\u7528\u4f5c\u8bc4\u4ef7\u7ebf\u7c92\u4f53\u751f\u7269\u80fd\u91cf\u529f\u80fd\u969c\u788d\u7684\u6807\u5fd7\u7269\u3002<strong>\u86cb\u767d\u8d28\u5370\u8ff9\u5206\u6790\u7ed3\u679c\u663e\u793a\uff0cCOX IV\u86cb\u767d\u8868\u8fbe\u6c34\u5e73\u5347\u9ad8\uff0c\u540c\u65f6Sod2\u548cCat\u86cb\u767d\u6c34\u5e73\u4e5f\u663e\u8457\u4e0a\u8c03\u3002<\/strong>\u8fd9\u79cd\u201c\u514d\u75ab\u8c03\u63a7\u2014\u7ebf\u7c92\u4f53\u7a33\u6001\u91cd\u5851\u201d\u7684\u53cc\u91cd\u8c03\u63a7\u673a\u5236\uff0c\u4e3aBMSCs\u7684\u6210\u9aa8\u5206\u5316\u63d0\u4f9b\u4e86\u5fc5\u9700\u7684\u80fd\u91cf\u57fa\u7840\u548c\u7a33\u5b9a\u7684\u6c27\u5316\u8fd8\u539f\u5fae\u73af\u5883\u3002<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-8093 size-full\" src=\"https:\/\/www.bio-oi.com\/wp-content\/uploads\/2026\/07\/21c9d39b75d23f1b0b514d96b4732b27.png\" alt=\"\" width=\"574\" height=\"835\" srcset=\"https:\/\/www.bio-oi.com\/wp-content\/uploads\/2026\/07\/21c9d39b75d23f1b0b514d96b4732b27.png 574w, https:\/\/www.bio-oi.com\/wp-content\/uploads\/2026\/07\/21c9d39b75d23f1b0b514d96b4732b27-206x300.png 206w\" sizes=\"auto, (max-width: 574px) 100vw, 574px\" \/><\/p>\n<section>\n<section><\/section>\n<h1 style=\"text-align: center;\"><strong><span style=\"font-family: arial, helvetica, sans-serif; font-size: 14pt; color: #3366ff;\">\u6587\u7ae0\u5b9e\u9a8c\u914d\u5957\uff1a\u8fd9\u7c7b\u8bfe\u9898\u7684WB\uff0c\u5982\u4f55\u7528OI600MF Touch\u505a\u5230\u201c\u7a33\u3001\u51c6\u3001\u5feb\u201d<\/span><\/strong><\/h1>\n<\/section>\n<section>\n<section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u8fd9\u7c7b\u5f31\u4fe1\u53f7WB\u5bf9\u6210\u50cf\u8bbe\u5907\u63d0\u51fa\u4e86\u4e09\u70b9\u6838\u5fc3\u8981\u6c42\uff1a\u7075\u654f\u5ea6\u3001\u7ebf\u6027\u533a\u548c\u591a\u6a21\u5f0f\u517c\u5bb9\uff0c\u800cOI600MF Touch\u80fd\u5f88\u597d\u7684\u6ee1\u8db3\u4ee5\u4e0a\u9700\u6c42\u3002<\/span><\/section>\n<section>\n<section>\n<section>\n<section>\n<section><span style=\"color: #ff9900;\"><strong><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u8bbe\u5907\u8981\u70b9\uff1a<\/span><\/strong><\/span><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><span style=\"color: #ff9900;\">\u2460<\/span> 900\u4e07\u50cf\u7d20\u6df1\u51b7\u79d1\u7814\u76f8\u673a\uff0c\u9ad8\u7075\u654f\u3001\u4f4e\u566a\u58f0\uff0c\u9002\u5408\u5f31\u4fe1\u53f7ECL\/\u5316\u5b66\u53d1\u5149\u4e0e\u5fae\u5f31\u8367\u5149\uff1b<\/span><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><span style=\"color: #ff9900;\">\u2461<\/span> F0.95\u5927\u5149\u5708\u81ea\u52a8\u5bf9\u7126\u955c\u5934\uff0c\u5f31\u4fe1\u53f7\u6761\u5e26\u8fdb\u5149\u91cf\u5145\u8db3\uff1b<\/span><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><span style=\"color: #ff9900;\">\u2462<\/span> \u5cf0\u503cQE\u53ef\u8fbe\u7ea695%\uff0c\u5728\u53ef\u89c1-\u8fd1\u7ea2\u5916\u6ce2\u6bb5\u90fd\u80fd\u9ad8\u6548\u6536\u5149\uff0c\u6697\u6761\u5e26\u4fe1\u53f7\u4e5f\u4e0d\u6d41\u5931\uff1b<\/span><\/section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><span style=\"color: #ff9900;\">\u2463<\/span>\u53ef\u9009\u914dRGB\u8367\u5149\u5149\u6e90\/\u7d2b\u5916\/\u767d\u5149\/ECL\u6837\u54c1\u53f0\uff0c\u8986\u76d6\u751f\u7269\u5316\u5b66\u53d1\u5149\u3001\u51dd\u80f6\u6210\u50cf\u3001\u591a\u8272\u8367\u5149\u3001\u5b54\u677f\u53d1\u5149\u7b49\u573a\u666f\u3002<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section><\/section>\n<section><\/section>\n<p>&nbsp;<\/p>\n<section>\n<section>\n<section>\n<section>\n<section><\/section>\n<h1 style=\"text-align: center;\"><strong><span style=\"font-family: arial, helvetica, sans-serif; font-size: 14pt; color: #3366ff;\">\u5168\u6587\u603b\u7ed3<\/span><\/strong><\/h1>\n<section>\n<section><\/section>\n<section><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section>\n<section><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\">\u53d7\u201c\u79f8\u79c6\u589e\u5f3a\u9ecf\u571f\u201d\u7ed3\u6784\u542f\u53d1\uff0c\u672c\u7814\u7a76\u8bbe\u8ba1\u4e86\u4e00\u79cd\u6d3b\u6027\u6c27\uff08ROS\uff09\u54cd\u5e94\u6027\u590d\u5408\u6c34\u51dd\u80f6\uff08EM@mSF-AP\uff09\uff0c\u7528\u4e8e\u7cd6\u5c3f\u75c5\u9aa8\u7f3a\u635f\u4fee\u590d\u3002\u8be5\u6c34\u51dd\u80f6\u4ee5\u787c\u9178\u916f\u952e\u6784\u5efa\u4ea4\u8054\u7f51\u7edc\uff0c\u63ba\u5165\u77ff\u5316\u4e1d\u7d20\u86cb\u767d\u77ed\u7ea4\u7ef4\uff08mSF\uff09\u4ee5\u589e\u5f3a\u529b\u5b66\u6027\u80fd\uff0c\u5e76\u8d1f\u8f7dEGCG-Met\u7eb3\u7c73\u7c92\uff08EM NPs\uff09\u3002\u5728\u7cd6\u5c3f\u75c5\u9ad8ROS\u5fae\u73af\u5883\u4e2d\uff0c\u6c34\u51dd\u80f6\u54cd\u5e94\u6027\u91ca\u653eEM NPs\uff0c\u6e05\u9664ROS\uff0c\u8bf1\u5bfc\u5de8\u566c\u7ec6\u80de\u5411M2\u8868\u578b\u6781\u5316\uff0c\u4ece\u800c\u9a71\u52a8\u514d\u75ab-\u6210\u9aa8\u7ea7\u8054\u53cd\u5e94\uff0c\u7cfb\u7edf\u6027\u6062\u590d\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08BMSCs\uff09\u7684\u7ebf\u7c92\u4f53\u7a33\u6001\uff1a\u6fc0\u6d3bSod2-Cat\u6297\u6c27\u5316\u8f74\u3001\u6062\u590d\u7ebf\u7c92\u4f53\u819c\u7535\u4f4d\u4e0e\u52a8\u529b\u5b66\u7a33\u5b9a\u6027\u3001\u4e0a\u8c03COX IV\u8868\u8fbe\u5e76\u91cd\u5efa\u9ad8\u6548\u80fd\u91cf\u4ee3\u8c22\u3002\u540c\u65f6\uff0cmSF\u91ca\u653e\u7684Sr\u00b2\u207a\/Ca\u00b2\u207a\u79bb\u5b50\u534f\u540c\u4fc3\u8fdb\u8840\u7ba1\u751f\u6210\u4e0e\u6210\u9aa8\u5206\u5316\u3002\u52a8\u7269\u5b9e\u9a8c\u8868\u660e\uff0c\u8be5\u6c34\u51dd\u80f6\u5728\u7cd6\u5c3f\u75c5\u5927\u9f20\u9885\u9aa8\u7f3a\u635f\u6a21\u578b\u4e2d\u663e\u8457\u6539\u5584\u514d\u75ab\u5fae\u73af\u5883\u3001\u589e\u5f3a\u80fd\u91cf\u4ee3\u8c22\u3001\u4fc3\u8fdb\u65b0\u9aa8\u5f62\u6210\u3002<strong>\u8be5\u7814\u7a76\u63d0\u51fa\u7684\u201c\u514d\u75ab\u8c03\u63a7\u2014\u7ebf\u7c92\u4f53\u7a33\u6001\u6062\u590d\u2014\u6210\u9aa8\u8026\u5408\u201d\u7ea7\u8054\u6cbb\u7597\u7b56\u7565\uff0c\u4e3a\u7cd6\u5c3f\u75c5\u9aa8\u518d\u751f\u63d0\u4f9b\u4e86\u5177\u6709\u524d\u666f\u7684\u65b0\u578b\u6750\u6599\u4e0e\u7406\u8bba\u4f9d\u636e\u3002<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-family: arial, helvetica, sans-serif; font-size: 12pt;\"><strong>\u53c2\u8003\u6587\u732e\uff1a<\/strong>Li, Y.; Cui, Z.; Liao, H.; Han, X.; Guo, K.; Xia, Z.; Cai, R.; Zhao, D.; Tao, G. A Straw-Reinforced-Clay-Inspired Composite Hydrogel Promotes Diabetic Bone Regeneration via Driving the Immune-Osteogenic Cascade to Remodel Mitochondrial Homeostasis.\u00a0ACS Nano\u00a02026, DOI: 10.1021\/acsnano.6c02616.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8fd1\u671f\u4e00\u9879\u7814\u7a76\u663e\u793a\u53d7\u201c\u79f8\u79c6\u589e\u5f3a\u9ecf\u571f\u201d\u7ed3\u6784\u542f\u53d1\uff0c\u8bbe\u8ba1\u4e86\u4e00\u79cd\u6d3b\u6027\u6c27\uff08ROS\uff09\u54cd\u5e94\u6027\u590d\u5408\u6c34\u51dd\u80f6\uff08EM@mSF-AP\uff09\uff0c [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"footnotes":""},"categories":[93,90],"tags":[],"class_list":["post-8086","post","type-post","status-publish","format-standard","hentry","category-kjiu","category-newcenter"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.bio-oi.com\/index.php?rest_route=\/wp\/v2\/posts\/8086","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bio-oi.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bio-oi.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bio-oi.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bio-oi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8086"}],"version-history":[{"count":7,"href":"https:\/\/www.bio-oi.com\/index.php?rest_route=\/wp\/v2\/posts\/8086\/revisions"}],"predecessor-version":[{"id":8096,"href":"https:\/\/www.bio-oi.com\/index.php?rest_route=\/wp\/v2\/posts\/8086\/revisions\/8096"}],"wp:attachment":[{"href":"https:\/\/www.bio-oi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8086"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bio-oi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8086"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bio-oi.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8086"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}